Endocrine Abstracts

Background and aim: Obesity (Ob) is tightly associated with metabolic diseases such as type 2 diabetes (DT2) andinsulin resistance (IR). Furthermore, obesity has been identified as one of the primary causes of mood disorders (MDs) including depression. Several studies have demonstrated the link between Ob, adiposity, neuroinflammation and MDs. The Brain-Derived Neurotrophic Factor (BDNF) and its regulator, the non-coding RNA BDNF antisense RNA (BDNFas), play an import...

Background and aimMajor depressive disorder (MDD) is one of the common mental disorder that affect more than 350 million subjects. MDD has been reported to be associated with systemic inflammation and obesity. However, there are no data that relate adipose tissue (AT) inflammation to MDD. The analysis of inflammatory markers in AT could pave the way to clarify the potential association between MDD and obesity. For this reason, the aim of our study was to...

Introduction: Adrenal vein sampling (AVS) is the gold standard test to distinguish between unilateral adenoma and bilateral hyperplasia in primary hyperaldosteronism. This is a technical complicated procedure with a variable success rate. Our aim was to report our 10-year-success rate and results as regards to this procedure.Material and Methods: Retrospective observational study including data from patients undergoing AVS between 2009 and 2019.<p cl...

IntroductionSemaglutide is a glucagon-like peptide-1 receptor agonist which has shown important benefits in patients with type 2 diabetes mellitus (T2DM) in randomized clinical trials. Its commercialization in Spain began in May of 2019. The main purpose of this study was to analyze the effectiveness of this drug into routine clinical practice in patients with T2DM with a body-mass index above 30 kg/m2.Matherial and meth...